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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG3
All Species:
11.82
Human Site:
S527
Identified Species:
21.67
UniProt:
Q96JB2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB2
NP_113619.1
828
94096
S527
L
E
E
G
E
S
N
S
L
T
K
S
G
S
T
Chimpanzee
Pan troglodytes
XP_001158886
790
89707
Q500
V
M
M
E
Q
I
A
Q
S
L
K
D
E
Q
K
Rhesus Macaque
Macaca mulatta
XP_001096875
828
94056
S527
L
E
E
G
E
S
N
S
L
T
K
S
G
S
T
Dog
Lupus familis
XP_848489
830
94828
N529
L
E
E
T
E
S
N
N
L
T
K
S
G
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI04
820
93264
G519
L
E
E
G
E
A
S
G
L
R
K
S
G
S
T
Rat
Rattus norvegicus
NP_001012157
828
94228
S527
L
E
E
G
E
S
S
S
L
R
K
S
G
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417041
835
94848
N524
L
E
D
P
E
S
C
N
L
V
K
S
G
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137512
820
93798
E520
S
F
S
D
V
Q
L
E
E
S
E
N
K
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q961G1
905
101221
S515
N
S
M
V
S
S
V
S
S
A
V
E
T
E
S
Honey Bee
Apis mellifera
XP_393867
799
92557
I493
D
D
N
I
L
E
P
I
S
R
N
H
I
E
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196648
781
87158
M499
E
G
M
R
S
T
V
M
A
P
I
G
S
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177485
784
88591
T489
K
L
E
G
S
P
N
T
T
S
E
T
D
L
R
Baker's Yeast
Sacchar. cerevisiae
P40094
801
92526
L504
S
F
K
N
R
S
I
L
P
I
S
P
N
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.9
95
N.A.
94.9
96.2
N.A.
N.A.
86.4
N.A.
77
N.A.
40.2
41.5
N.A.
47.5
Protein Similarity:
100
95.4
99.7
97.1
N.A.
96.9
98.1
N.A.
N.A.
92.5
N.A.
87
N.A.
56.4
60.5
N.A.
63.1
P-Site Identity:
100
6.6
100
86.6
N.A.
73.3
86.6
N.A.
N.A.
60
N.A.
0
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
20
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
73.3
N.A.
20
N.A.
20
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
0
8
8
0
0
0
0
24
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
0
0
0
0
0
0
8
8
8
0
% D
% Glu:
8
47
47
8
47
8
0
8
8
0
16
8
8
16
0
% E
% Phe:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
39
0
0
0
8
0
0
0
8
47
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
8
0
8
8
8
0
8
8
0
8
0
0
% I
% Lys:
8
0
8
0
0
0
0
0
0
0
54
0
8
8
8
% K
% Leu:
47
8
0
0
8
0
8
8
47
8
0
0
0
8
8
% L
% Met:
0
8
24
0
0
0
0
8
0
0
0
0
0
0
8
% M
% Asn:
8
0
8
8
0
0
31
16
0
0
8
8
8
0
0
% N
% Pro:
0
0
0
8
0
8
8
0
8
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
8
0
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
8
8
0
0
0
0
24
0
0
0
0
8
% R
% Ser:
16
8
8
0
24
54
16
31
24
16
8
47
8
47
8
% S
% Thr:
0
0
0
8
0
8
0
8
8
24
0
8
8
0
39
% T
% Val:
8
0
0
8
8
0
16
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _